Reproduction of the Prague Golem. [Image from the Wikipedia 'Golem' page, public domain, via Wikimedia Commons.]
In Jewish folklore, a golem is an animated anthropomorphic being, created entirely from inanimate matter. The word was used to mean an amorphous, unformed material in Psalms and medieval writing. The most famous golem narrative involves Judah Loew ben Bezalel, the late-16th-century rabbi of Prague. There are many tales differing on how the golem was brought to life and afterwards controlled.
The earliest stories of golems date to early Judaism. Early on, the main disability of the golem was its inability to speak.[a] Recall that Hannibal is essentially mute for a period of time, i.e., in the orphanage (above left), up until he has been with Lady Murasaki for a while (above right).
Part of the golem legend sometimes depicts the golem as eventually becoming evil, turning on society. By the end of Hannibal Rising, Hannibal has obviously become evil. In the Lecter movies that are set later than Hannibal Rising (The Silence of the Lambs, etc.) it becomes evident that Lecter, as a full adult, has turned on society, symbolizing the fact that this is what the evil hermaphroditic Jews have done.
a. Wikipedia, 'Golem'. Web, n.d. URL = https://en.wikipedia.org/wiki/Golem.