It is not difficult to see how Reba is portrayed as both a virgin and a 'whore' in the movie. When Dollarhyde offers to give her a ride home from work, with a "surprise" on the way (this turns out to be the tiger visit), she refuses several times, then relents. This can be interpreted as a promiscuous woman 'playing hard to get', but not being afraid to ride with a strange man, as if she has done so before (i.e., with other men besides Dollarhyde); or, it can be interpreted as the 'innocence' of a virgin, of someone not experienced in dating - she naively fails to consider that riding with a stranger could be dangerous.
Above left and right: Once Reba has been in Dollarhyde's house for a while, the 'whore' within her may seem to take over, but even her initiation of the sexual interaction between them could be seen as part of the first love-making experience of an innocent woman - she does not consider it improper to seduce him.
Dollarhyde later comes to see Reba as a whore, due to the fact that he misinterprets her interaction with another man (Ralph Mandy) as having sexual overtones, as shown in the below screencaps.
Top left: Francis, who has been waiting outside Reba's house without her knowing it, is initially excited upon seeing her arrive home. He begins to get out of his van to greet her, but then notices that she is with Ralph Mandy. Top right: Mandy removes a piece of something from Reba's cheek. Above left: This is how Francis interprets the interaction between Mandy and Reba. Above right: Francis's anguished reaction at what he thinks he has seen.
Dollarhyde's reaction to seeing Reba with Mandy, is to kidnap her and hold her in his house, where, as shown in the below screencap, he stands over her menacingly as if about to kill her.
Francis standing over Reba near the movie's ending.